Glycolic Acid, Arbutin and Kojic Acid Dipalmitate Cream: Ultimate Skin Brightening Formula
Release time: 2025-10-09
Kojic Acid Dipalmitate (KAD) is an esterified derivative of kojic acid that serves as a powerful depigmenting agent for skincare. Unlike kojic acid, KAD is fat-soluble and highly stable (resistant to light, heat, and oxidation), making it ideal for cosmetic creams and serums. KAD effectively inhibits melanin production by blocking the enzyme tyrosinase, leading to brighter, more even skin tone. It also offers antioxidant benefits, protecting skin from free-radical damage. Together with complementary actives like glycolic acid and arbutin, KAD forms a synergistic brightening system.
- Intense Brightening:KAD, a powerful tyrosinase inhibitor, reduces the appearance of dark spots and hyperpigmentation. It works synergistically with arbutin (another melanin blocker) and glycolic acid (an exfoliating ingredient) to reveal a radiant complexion and even skin tone.
- Superior Stability: KAD is far more stable than kojic acid, resisting oxidation and color change. It remains effective over time and across a wide pH range.
- Oil-Soluble Compatibility: As an oil-soluble active ingredient, KAD blends seamlessly into the oil phase of lotions, creams, and sunscreens. This broad compatibility means it can be used with glycolic acid, arbutin, niacinamide, and other commonly used skin-lightening ingredients without compromising their effectiveness.
- Enhanced Skin Health: Besides lightening, KAD provides antioxidant and moisturizing properties, which can improve skin texture and help prevent premature aging.

Glycolic Acid, Arbutin and KAD Cream: Synergistic Benefits
Creams that combine glycolic acid, arbutin, and Kojic Acid Dipalmitate deliver comprehensive brightening and rejuvenation. Glycolic acid (an AHA) exfoliates dead skin cells, revealing fresh epidermis. Meanwhile, arbutin and KAD penetrate deeper to inhibit melanin synthesis and fade dark spots. The Zeeglow cream, for example, touts “enhanced radiance” and “reduced dark spots” by leveraging this trio. Regular use results in noticeably smoother, more luminous skin as discoloration is corrected from within. In essence, these skin brightening active ingredients (glycolic, arbutin, KAD) act together:
- Exfoliation: Glycolic acid removes dull surface cells, improving texture.
- Melanin Suppression: Arbutin and Kojic Acid Dipalmitate block tyrosinase, preventing new pigment formation.
- Hydration & Repair: Many formulations also include moisturizers (e.g., niacinamide, vitamin E) to soothe and repair skin.
The result is an even, radiant complexion with fewer spots. This combination is especially popular in markets where brightening and anti-aging are in demand.
For more information on whitening formulas, please contact BLi-T Chemical for more technical information and formula support.
How to Dissolve Kojic Acid Dipalmitate Powder
KAD powder is insoluble in water but readily dissolves in oils and glycol-based solvents. To prepare it for your cream:
- Oil Phase Incorporation: Predissolve KAD in a suitable oily or oily solvent. Suitable carriers include isopropyl palmitate, isopropyl myristate, or natural esters. Heat the oil phase to approximately 80°C while stirring; the KAD will dissolve into the oil.
- Alternative Solvents: Some formulators dissolve KAD in propylene glycol or specialized solubility enhancers. After full dissolution, the oil (or solvent) phase is then added to the water phase.
- Stirring and Heating: Maintain gentle heat and vigorous stirring until the powder fully disappears. For example, mixing 3–5 g of KAD powder in 100 mL of oil-based cream and stirring until clear has been shown to work effectively.
This method prevents crystal precipitation. For water-based emulsions, first mix the KAD into the oil phase (possibly with a cosolvent), then emulsify. Keeping the oil phase warm and well-stirred will help the KAD fully incorporate. In short, for best results, always dissolve the KAD in the oil (lipid) portion of the formulation.
How to Use Kojic Acid Dipalmitate Powder
In finished products, Kojic Acid Dipalmitate is typically used at 1–5% concentration. Most effective brightening is seen at the higher end of that range: many sources recommend 3–5% for topical creams (1–2% can be too mild). Here are key usage tips:
- Usage Level: Start around 1–3% for gentle brightening; increase to 3–5% if formulating for stronger depigmenting effects. BLi-T (Hefei) data notes typical use up to 5%.
- Formulation Phase: Add KAD to the oil phase of an emulsion. Because it’s oil-soluble, it won’t mix directly into the water phase.
- Solubility/Stability: KAD is stable in the formula once emulsified. It tolerates a broad pH range and can coexist with most cosmetic actives. (However, avoid very high-acid formulas – a buffered, mild pH is best for skin.)
- Product Types: KAD can be used in lotions, creams, serums, masks, and even sunscreens. It’s often included in both leave-on brightening products and rinse-off treatments.
Always follow good manufacturing practices: protect the KAD-containing formula from excessive heat or light during production, and store finished products in a cool, dry place to preserve potency.
Is Kojic Acid Dipalmitate Safe for Skin?
Yes, Kojic Acid Dipalmitate is generally considered safe and well-tolerated in cosmetic use, especially compared to pure kojic acid. As an ester of kojic acid, KAD is neutral (non-acidic) and gentler on the skin. Clinical experience suggests it causes less irritation than free kojic acid. In fact, some experts note that formulations containing KAD tend to be milder, since KAD does not form hydrogen bonds with skin proteins and is less likely to oxidize or discolor the formula.
Of course, as with any active, patch-testing on sensitive skin is wise. Most users should not experience significant irritation at recommended levels. Regulatory assessments (e.g. on kojic acid usage) often cite 1–2% for safety, but KAD’s improved profile allows up to 3% or higher in many cosmetics. Always adhere to cosmetic safety guidelines: avoid using multiple strong exfoliants or irritants together, and label the product for external use only. In summary, when formulated correctly, KAD is a safe depigmenting agent that delivers potent brightening without undue risk.This makes kojic acid palmitate particularly popular among well-known cosmetics at home and abroad, such as Proya, Winona, DrJohom, Decorte, Shiseido, SkinCeuticals,etc.
BLi-T (Hefei) Chemical Co., Ltd – Premium KAD Supplier
BLi-T (Hefei) Chemical Co., Ltd. is a leading supplier of high-purity Kojic Acid Dipalmitate. Established in 2017, BLi-T focuses on “providing high-quality chemicals to customers at competitive prices and offering customized services”. Key features of BLi-T’s KAD offering include:
- High Purity: Our KAD powder is ≥99% pure (HPLC), BP/USP grade. This ensures maximum efficacy and low impurities in finished creams.
- Full Documentation: Technical Data Sheets (TDS), Material Safety Data Sheets (MSDS), and Certificates of Analysis (COA) are available. Customers can download or request these files to verify quality.
- Solubility & Stability Support: We assist formulators with solubility tips and stability data. For example, guidance on oil-phase incorporation and recommended concentrations is provided, ensuring KAD blends well with glycolic acid, arbutin, and other actives.
- Packaging & Logistics: KAD is supplied in 25 kg drums (or custom packages) with robust packaging to prevent moisture ingress. BLi-T handles export logistics worldwide, serving customers in over 150 countries].
- OEM/Bulk Supply: Whether you need small R&D samples or multi-ton orders for OEM production, BLi-T scales to your needs. A professional sales and service team supports pre-sales formulation questions and after-sales technical issues.
With BLi-T’s Kojic Acid Dipalmitate powder, cosmetic companies gain a reliable ingredient backed by rigorous quality control and documentation. This enables speedy product development and faster time-to-market for brightening skincare lines.
Market Trends and Compatibility
The demand for skin-brightening active ingredients continues to surge globally. Market research shows rapid growth in brightening products, especially in Asia-Pacific and Europe. Consumers increasingly prefer “natural” or bio-derived actives with proven safety. KAD, derived from kojic acid (a natural fungal byproduct), fits this trend. Key market insights:
- Growing Demand: The kojic acid market is projected to reach ~$59 million by 2030, driven by skincare and cosmetics. Sales of brightening creams and serums are rising as consumers seek solutions for hyperpigmentation.
- Ingredient Trends: Popular skin lighteners now include glycolic acid, arbutin, niacinamide, tranexamic acid – and KAD is emerging as a premium derivative of kojic acid. Its stability and effectiveness make it attractive for formulators.
- Product Synergy: Multi-ingredient formulas (e.g. combining KAD with other tyrosinase inhibitors and exfoliants) are on-trend, as they can deliver faster, synergistic results.
From a formulation perspective, KAD’s compatibility is a major advantage. It’s suitable for a wide range of formulations: water-in-oil creams, oil-in-water emulsions, anhydrous serums, and even sunscreen lotions. Because KAD is oil-soluble and light- and heat-stable, unlike kojic acid, it’s not susceptible to degradation or discoloration. This means formulators can safely combine it with other brighteners without significant stability issues.
Overall, the combination of rising market interest in brightening agents and KAD’s favorable properties positions glycolic acid + arbutin + KAD creams as a hot trend. Formulators adopting this trio – backed by a reliable supplier like BLi-T – can meet growing consumer demand for effective, safe, and natural depigmenting products.Email to info@blitchem.com to get more information
FAQs (For Cosmetic Formulators and Skincare Businesses)
- Q: How do I incorporate Kojic Acid Dipalmitate powder into my formulation?
- A: Dissolve KAD in the oil phase of your formula. As outlined, mix KAD into heated oils or emulsifier blend (e.g. isopropyl palmitate) at ~80°C, stirring until fully dissolved. Then add this oil phase to your water phase. Target a usage level of 1–5% KAD; many successful formulas use 3–5% for visible brightening. Ensure thorough mixing to avoid particles.
- Q: What technical documents and support does BLi-T provide for Kojic Acid Dipalmitate?
- A: BLi-T offers comprehensive documentation: TDS, MSDS, and COA for each KAD batch. Customers can download these files or request them via email. Additionally, BLi-T’s technical team provides formulation advice, helping customers with solubility strategies and stability data to ensure KAD works effectively in products.
- Q: Is Kojic Acid Dipalmitate suitable for B2B/OEM cosmetics production, and is it safe?
- A: Yes. BLi-T CHEMICAL’s high-purity KAD powder (≥99%) is produced under strict quality control, ideal for large-scale B2B or OEM use. Kojic Acid Dipalmitate is well-established in cosmetics – it’s considered safer and more stable than kojic acid. When used at recommended levels (typically ≤5%), it is generally non-irritating. For sensitive skin formulas, use the lower end of the concentration range. Always validate safety via product testing and patch tests, but KAD’s profile makes it a safe depigmenting agent for commercial skincare products.

