Dichlorobenzyl Alcohol DCBA CAS 1777-82-8

BLIT Chemical Dichlorobenzyl Alcohol CAS 1777-82-8 is a well-known antimicrobial and antiseptic active ingredient widely used in oral care, pharmaceutical, and healthcare formulations. As a professional manufacturer and supplier of pharmaceutical-grade actives, BLIT Chemical provides Dichlorobenzyl Alcohol with consistent purity and reliable performance.

Dichlorobenzyl Alcohol typically appears as a white to off-white crystalline solid with a mild characteristic odor. It exhibits good stability under normal storage conditions and demonstrates strong antibacterial activity against a broad spectrum of Gram-positive and Gram-negative microorganisms. Due to its proven efficacy and regulatory acceptance, it is commonly incorporated into throat lozenges, mouthwashes, sprays, and other oral hygiene products.

Chemically, Dichlorobenzyl Alcohol belongs to the aromatic alcohol family and functions by disrupting microbial cell membranes, thereby inhibiting bacterial growth. Its balanced solubility profile allows it to be formulated effectively with other active ingredients such as amylmetacresol, menthol, and flavoring agents. BLIT Chemical Dichlorobenzyl Alcohol is produced under controlled conditions to meet pharmaceutical and oral-care formulation requirements.

Specification

BLIT CHEM Dichlorobenzyl Alcohol Applications

Oral Care Applications

Dichlorobenzyl Alcohol is most widely recognized for its use in oral healthcare:

• Antibacterial agent in throat lozenges
• Active ingredient in mouthwashes and oral sprays
• Helps relieve sore throat and oral infections
• Works synergistically with other antiseptics

Dichlorobenzyl Alcohol can also be added to shampoos as an additive to enhance dandruff control.

Why manufacturers choose BLIT Chemical Dichlorobenzyl Alcohol

• R&D: Our core I&R team possesses extensive innovative R&D experience in areas such as active small molecule development, plant extraction, and bio-fermentation. Furthermore, the addition of numerous outstanding young R&D personnel brings us more innovative ideas and research directions.
• manufacturer: Our factory is equipped with hardware facilities strictly adhering to GMP standards, including a Class 100,000 cleanroom. Advanced automated production equipment effectively prevents errors and reduces contamination. The production process strictly follows GMP regulations, including material management, factory hygiene, operator training, production processes, quality control, and related document management.
• Testing: A fully equipped QC laboratory is used for testing the quality of our products. Our independent skincare product functionality research and testing evaluation center, covering over 2,000 square meters, is a national-level P2 laboratory built according to the national standard GB19498-2011 <<General Requirements for Laboratory Microbiological Safety>>, and has obtained China CMA certification. Testing scope covers physicochemical testing, microbiological testing, human efficacy, and sensory evaluation.
• Sales: Through years of channel building and market deployment, our high-quality products are consistently and stably sold worldwide.

Storage & Handling

Store in a cool, dry, and well-ventilated area. Keep the container tightly closed and protected from moisture and direct sunlight.

Safety Guidelines

Acute and subacute toxicity

• The acute LD50 of dichlorobenzyl alcohol in rats is 3000 mg/kg, and the acute LD50 in mice is 2300 mg/kg. According to the acute toxicity classification standard, it is classified as a low-toxicity substance.
• Rats were administered 500 mg/kg orally for 3 weeks, and guinea pigs were administered 1.2 mg/(kg·d) orally for 4 weeks. The toxicity results were negative in both cases.

Irritating

• Guinea pig skin irritation tests showed that 1% dichlorobenzyl alcohol did not cause irritation, while 5% did.
• Normal individuals showed no irritation after continuous use of a face cream containing 2.5% dichlorobenzyl alcohol for 8 days; however, application to broken skin caused a slight stinging sensation.
• Rabbit eye irritation tests showed that 0.05% and 0.1% dichlorobenzyl alcohol did not cause eye irritation 2 hours after application, while concentrations of 0.5% and 1% caused mild irritation.

Allergenicity

• Formulations containing 2% (acetone as solvent), 0.1% (water as solvent), and 2.5% (cream) of dichlorobenzyl alcohol did not cause sensitization reactions in guinea pig skin.
• A Swiss contact dermatitis research group conducted a year-long study on 13 common preservatives, evaluating 2295 patients suspected of having allergic contact dermatitis. The results showed that dichlorobenzyl alcohol had a lower sensitization rate than preservatives such as benzalkonium chloride, chlorhexidine, nipaquinone, DP300, and germ.

Teratogenicity

• Rabbits were given dichlorobenzyl alcohol orally at a dose of 20 mg/(kg·d), and the results were negative.

The above content was compiled by the BLIT CHEMICAL technical team based on their research and review of relevant literature.

Use Guidelines

• Recommended dosage: 0.01~0.15% (≤0.15%)
• Processing: First disperse with a portion of the polyol, then dissolve in water at 65°C.
• Applications: Hair products (antibacterial and anti-dandruff), dental care (inhibits dental plaque microorganisms), facial care, disinfectants, etc.

Packaging

25 kg fiber drums or cartons, or customized packaging according to customer requirements.